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Revolving Credit Facility [Member] Revolving Credit Facility [Member] Net loss per share attributable to common stockholders, basic Net income (loss) per share applicable to common stockholders - basic Earnings Per Share, Basic, Total Earnings Per Share, Basic Net loss per share attributable to common stockholders - basic Inventory Written- down Inventory Written- down Inventory Write-down Commitments and contingencies (Note 15) Commitments and Contingencies Business Combinations [Abstract] Property, Plant and Equipment Disclosure [Text Block] Property and Equipment, Net Related Party, Type [Axis] Related Party Deferred income - related party Deferred Income Deferred Income, Ending Balance Deferred Income, Beginning Balance Performance Shares [Member] Performance Shares [Member] Issuance of warrants, Shares Adjustments To Additional Paid In Capital, Warrant Issued Adjustments to Additional Paid in Capital, Warrant Issued Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block] Changes in Contract Liabilities Operating lease costs Operating Lease, Cost Short-term lease costs Short-Term Lease, Cost Restructuring Type [Axis] Number of Shares, Vested or expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Statistical Measurement [Domain] Net Cash Provided by (Used in) Operating Activities Cash used in operations Cash used in operating activities Net operating cash outflows Net cash used in operating activities Hercules credit facility [member]. 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Additional Paid in Capital, Common Stock Additional paid-in capital Additional Paid in Capital, Common Stock, Beginning Balance Additional Paid in Capital, Common Stock, Ending Balance Net (decrease) in cash, cash equivalents, and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect Inventories Inventory, Policy [Policy Text Block] Summary of Future Principal Payments Due Under the Oaktree Credit Arrangement, Excluding Interest and End of Term Charge Schedule of Maturities of Long-Term Debt [Table Text Block] Equity, Fair Value Disclosure [Abstract] Sublease agreement. Sublease Agreement [Member] Sublease Agreement [Member] 2029 and thereafter Lessee Operating Lease Liability To Be Paid After Year Four Lessee operating lease liability to be paid after year four. Tranche A warrant. Tranche A Warrant [Member] Tranche A Warrant [Member] Schedule of Restructuring and Related Costs [Table] Dilutive impact from: Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract] Investment, Type [Extensible Enumeration] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Issuance of common stock upon exercise of stock options, shares Number of Shares, Exercised Stock issued during period shares at market equity offerings. Stock Issued During Period Shares At Market Equity Offerings Issuance of common stock from at the market equity offering, shares Research and development fixed consideration. Research And Development Fixed Consideration Research and development fixed consideration Liabilities and Equity [Abstract] Liabilities and Stockholders (Deficit) Equity Secured Overnight Financing Rate Sofr [Member] Secured overnight financing rate SOFR. Secured Overnight Financing Rate SOFR [Member] SOFR [Member] Notice period for termination of agreement. Notice Period For Termination Of Agreement Termination notice period Debt Conversion, Converted Instrument, Warrants or Options Issued Debt instrument conversion warrants or options issued Entity Address, Postal Zip Code Entity Address, Postal Zip Code Entity Interactive Data Current Entity Interactive Data Current Phase two study. Phase Two Study [Member] Phase 2 [Member] Sales agreement. Sales Agreement [Member] Sales Agreement [Member] Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accounts Payable, Total Revenue, Product and Service [Extensible Enumeration] Type of Revenue [Extensible List] Credit Facility [Domain] Credit Facility Real Estate [Domain] Option exercise period from exclusivity period. Option Exercise Period From Exclusivity Period Option exercise period from exclusivity period Equity [Abstract] Less: interest Less: interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Employee Two [Member] Employee Two [Member] Employee two. Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Number of shares granted Number of Shares, Granted Current liability. Current Liability [Member] Current Liability [Member] Weighted Average Exercise Price, Exercised Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Entity incorporation, state or country code Research collaboration and option agreement. Research Collaboration And Option Agreement [Member] Research Agreement [Member] Basic Earnings Per Share: Earnings Per Share, Basic [Abstract] Terms of the definitive license agreement good faith negotiation period. Terms Of Definitive License Agreement Good Faith Negotiation Period Terms of the definitive license agreement good faith negotiation period Equity Components [Axis] Equity Components Restructuring and Related Activities [Abstract] Investments, Debt and Equity Securities [Abstract] Tenant improvement allowance Payments for Tenant Improvements Inventory Disclosure [Abstract] Total Liabilities [Member] Total liabilities. Total Liabilities [Member] Due from related party Other Receivables, Net, Current Other Receivables, Net, Current, Total Proceeds from Sale, Maturity and Collection of Investments Sales and maturities of investments Proceeds from Sale, Maturity and Collection of Investments, Total Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Vested Weighted Average Grant Date Fair Value, Vested Weighted average grant date fair value, vested Hercules lenders [member]. Hercules Lenders [Member] Hercules Lenders [Member] Local Phone Number Local Phone Number Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Sale of Stock [Axis] Sale of Stock Weighted Average Exercise Price, Options exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Nestle health science. Nestle Health Science [Member] Nestle Health Science [Member] Notes Payable, Current Short term portion of note payable, net of discount Notes Payable, Current, Total Statement of Cash Flows [Abstract] Operating lease right-of-use asset Impairment Right of Use Asset Impairment right of use asset. Organization, Consolidation and Presentation of Financial Statements [Abstract] Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income (loss) Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Proceeds from Collaborators Proceeds on achievement of development milestone Common Stock, Par or Stated Value Per Share Common stock, par value Common stock at a purchase price Service [Member] Service [Member] Cost associated with pre-launch activities Collaboration Arrangement, cost associated with pre-launch activities Collaboration arrangement, cost associated with pre-launch activities. Numerator: Net Income (Loss) Available to Common Stockholders, Basic [Abstract] Milestones payments received Milestones Payments Received Milestones payments received. Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset Weighted Average Remaining Contractual Term, Vested or expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Collaboration profit and loss Collaborative Arrangement Disclosure [Text Block] Maximum [Member] Maximum [Member] Anti-dilutive Potential Common Stock Equivalents Excluded from the Calculation of Net Income (Loss) Per Share Anti-dilutive potential common stock equivalents excluded from the calculation of net income (loss) per share. Anti-dilutive potential common stock equivalents excluded from the calculation of net loss per share Tranche D Loan [Member] Tranche D Loan. Tranche D Loan [Member] Debt Instrument, Convertible, Threshold Trading Days Trading days prior to the funding date Related Party Transaction [Axis] Related Party Transaction Collaboration (profit) loss sharing - related party Profit (Loss) from Research Agreements Related Party Profit (loss) from research agreements related party. Fair Value, Inputs, Level 3 [Member] Level 3 [Member] APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation expense APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Fair Value, Recurring and Nonrecurring [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Change in fair value of warrant liabilities Fair Value Adjustment of Warrants Payables and Accruals [Abstract] Research and development estimated reimbursement costs. Research And Development Estimated Reimbursement Costs Research and development estimated reimbursement costs Flagship Pioneering. Flagship Pioneering [Member] Flagship Pioneering [Member] General and administrative expenses [Member] General and Administrative Expenses [Member] General and Administrative Expense [Member] Noncash Investing and Financing Items [Abstract] Supplemental disclosure of non-cash investing and financing activities: Twenty twenty one license agreement. Twenty Twenty One License Agreement [Member] 2021 License Agreement [Member] Number of Shares, Forfeited Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Summary of Potential Common Shares Excluded from Calculation of Diluted Net Loss per Share Schedule of Capitalized Inventories Schedule of Inventory, Current [Table Text Block] Fair Value assets level 1 to level 2 transfers amount 1. 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Revenue [Member] Operating Income (Loss) [Member] Related Party Transactions Disclosure [Text Block] Related Party Transactions 2026 Lessee, Operating Lease, Liability, to be Paid, Year Two Statement [Line Items] Statement [Line Items] Prepayments on long term contract Prepayments On Long Term Contract Prepayments on a long term contract. Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Total common stock equivalents Anti-dilutive potential common stock equivalents excluded from the calculation of net loss per share: Phase 2b Study. Phase Two B Study [Member] Phase 2b [Member] Liabilities measured at fair value Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value Beginning Balance Ending Balance Total lease costs Lease, Cost Employee One [Member] Employee One [Member] Employee one. Warrants [Member] Warrant [Member] Shares issuable under employee stock purchase plan Incremental Common Shares Attributable To Dilutive Effect Of Share Issuable Under Employee Stock Purchase Plan Incremental Common Shares Attributable To Dilutive Effect Of Share Issuable Under Employee Stock Purchase Plan. Debt instrument additional advance prepayments percentage. Debt Instrument Additional Advance Prepayments Percentage Additional advance prepayment or repayment percentage Securities purchase agreement. Securities Purchase Agreement [Member] Securities Purchase Agreement [Member] Transaction price of milestone payment to be received. Transaction Price Of Milestone Payment To Be Received Transaction price of milestone payment to be received Warrants to purchase common stock Common Stock [Member] Common Stock [Member] Debt Instrument [Line Items] Debt Instrument [Line Items] Deferred revenue - related party, Deductions Contract with customer liability revenue recognized with related party. Contract With Customer Liability Revenue Recognized With Related Party Amounts included in the contract liability at the beginning of the period Deferred revenue - related party, Deductions Other Commitments [Table] Other Commitments [Table] Maximum amount to be received on achievement of sales milestones Maximum amount to be received on achievement of sales milestones. Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value, Total Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Ending Balance Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Summary of Stock Based Compensation Expense Corporate Bond Securities [Member] Corporate Bonds [Member] Aggregate Intrinsic Value, Options exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Accretion (Amortization) of Discounts and Premiums, Investments Net (accretion) amortization of (discounts) premiums on investments Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block] Summary of Stock Option Activity Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Deferred revenue - related party Increase (decrease) in contract with customer liability-related party. Increase (Decrease) in Contract with Customer Liability-Related Party Collaboration payable - related party (Note 17) Collaboration Payable Related Party Collaboration payable related party. Finished goods Inventory, Finished Goods, Gross Antidilutive Securities, Name [Domain] Antidilutive Securities, Name Manufacturing and quality costs Manufacturing and Quality Costs Manufacturing and quality costs. Operating Leased Assets [Line Items] Collaborative Arrangements Collaborative Arrangement, Accounting Policy [Policy Text Block] Interest Rate Cap [Member] Interest rate cap [Member] Cover [Abstract] Payments under agreements with related party Selling, General and Administrative Expense Selling, General and Administrative Expense, Total Lease amendment member. Lease Amendment [Member] Lease Amendment [Member] Accrued expenses and other current and long-term liabilities, related party amounts Accrued Expenses and Other current and Long-term Liabilities Related Party Amounts Accrued expenses and other current and long-term liabilities related party amounts. Vesting [Axis] Vesting Document Fiscal Year Focus Document Fiscal Year Focus Sale of Stock [Domain] Sale of Stock Laboratory space member. Laboratory Space [Member] Laboratory Space [Member] Option payment Option Payment1 Option payment. Weighted average grant-date fair value of stock options Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Granted Security Exchange Name Security Exchange Name Expiration period of stock options granted Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Total other comprehensive income (loss) Cash, Cash Equivalents and Restricted Cash Schedule of Cash and Cash Equivalents [Table Text Block] Recently Issued Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Debt Instrument Tranche Five [Member] Debt instrument tranche five. Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Issued, Total Preferred Stock, Shares Authorized Preferred stock, shares authorized Derivative liabilities Derivative Liability, Subject to Master Netting Arrangement, before Offset Bacthera [Member] Bacthera Agreement [Member] BacThera Agreement. BacThera Agreement [Member] Property, Plant and Equipment, Gross Property and equipment, gross Property, Plant and Equipment, Gross, Total Property, Plant and Equipment, Gross, Beginning Balance Property, Plant and Equipment, Gross, Ending Balance Weighted Average Exercise Price, Forfeited Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Business Acquisition, Acquiree [Domain] Financial Instrument [Axis] Summary of Restricted and Performance Stock Unit Activity Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock upon exercise of stock options, value Entity Emerging Growth Company Entity Emerging Growth Company Percentage of aggregate principal amount of term loan prepaid after the third anniversary of closing date. 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Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Gross Unrealized Loss Accounting Standards Update [Domain] Accounting Standards Update Restructuring Restructuring and Related Activities Disclosure [Text Block] Proceeds from Lines of Credit, Total Proceeds from Lines of Credit Net proceeds received from credit facility Collaborative Arrangement, Grant of License for Upfront Payment Collaborative Arrangement, Grant of License for Upfront Payment Collaborative arrangement, grant of license for upfront payment Fair Value, Option, Quantitative Disclosures [Line Items] Leases [Abstract] Variable Rate [Domain] Variable Rate Schedule of Changes in Restructuring Liability Schedule of Restructuring Reserve by Type of Cost [Table Text Block] Securities Act File Number Entity File Number Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table] Entity Addresses, Address Type [Axis] TrancheB Loan [Member] TrancheB Loan [Member] Tranche B Loan [Member] 2024 (remaining 9 months) Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Nature of business and basis of presentation. Nature Of Business And Basis Of Presentation [Line Items] Nature Of Business And Basis Of Presentation [Line Items] Cash equivalents original maturity maximum period. Cash Equivalents Original Maturity Maximum Period Maximum maturity days for cash equivalents Collaborative arrangement upfront license fee received. Collaborative Arrangement Upfront License Fee Received Upfront collaboration/license fee OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized gain (loss) on investments, net of tax of $0 Number of employees granted Number Of Employees Granted Number of employees granted. Total cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at end of period Cash, cash equivalents and restricted cash at beginning of period Share-Based Payment Arrangement [Abstract] Minimum exclusivity period. Minimum Exclusivity Period Minimum exclusivity period Accounts Payable, Current Accounts payable Accounts Payable, Current, Total Debt Instrument [Axis] Debt Instrument Employee Stock Option Market Condition [Member] Employee Stock Option Market Condition [Member] Employee Stock Option Market Condition [Member] Weighted Average Grant Date Fair Value, Unvested restricted stock units, Ending balance Weighted Average Grant Date Fair Value, Unvested restricted stock units, Beginning balance Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Operating Expenses Total operating expenses Line of credit facility exit fee percentage. Line of Credit Facility Exit Fee Percentage Line of credit facility exit fee percentage 2025 Long-Term Debt, Maturity, Year One Term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Oaktree fund administration, llc. Oaktree Fund Administration, LLC [Member] Oaktree Fund Administration, LLC [Member] Preferred stock, $0.001 par value; 10,000,000 shares authorized at March 31, 2024 and December 31, 2023; no shares issued and outstanding at March 31, 2024 and December 31, 2023 Preferred Stock, Value, Issued Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Ending Balance Entity Small Business Entity Small Business Entity Shell Company Entity Shell Company Percentage of prepayment amount during second year following closing date. Percentage Of Prepayment Amount During Second Year Following Closing Date Percentage of prepayment amount during second year Title of Individual [Axis] Investment Type [Axis] Class of Warrant or Right, Exercise Price of Warrants or Rights Warrants exercise price Payments to Acquire Investments Purchases of investments Payments to Acquire Investments, Total Certificates of Deposit [Member] Certificates of Deposit [Member] Issuance of common stock upon vesting of RSUs and PSUs, net of tax withholdings Restricted Stock, Shares Issued Net of Shares for Tax Withholdings Computer Equipment [Member] Computer Equipment [Member] Earnings Per Share [Text Block] Net Loss per Share Revenues [Abstract] Revenue: Entity incorporation month and year of incorporation. Entity Incorporation Month And Year Of Incorporation Entity incorporated month and year Commercial Paper [Member] Commercial Paper [Member] Entity Address, Address Line One Entity Address, Address Line One Cash and Cash Equivalents, Fair Value Disclosure Cash equivalents Contractual Obligation Obligations accrued Contractual Obligation, Total Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Antidilutive Securities [Axis] Antidilutive Securities Related parties, current Other Liabilities, Current Gross proceeds from issuance of common stock. Gross Proceeds From Issuance Of Common Stock Gross proceeds from sale of common stock Interest Rate During Period Debt Instrument, Interest Rate During Period Subsequent Event Type [Domain] Loan and security agreement. Loan And Security Agreement [Member] Loan and Security Agreement [Member] Maximum amount to be received on achievement of regulatory and sales milestones Maximum Amount To Be Received On Achievement Of Regulatory and Sales Milestones Maximum amount to be received on achievement of regulatory and sales milestones. RSU and PSU [Member] Restricted Stock Units And Performance Stock Units [Member] Restricted Stock Units and Performance Stock Units. Fourth Tranche Available Upon Satisfaction of Conditions Including Approval by U.S. Food and Drug Administration [Member] Debt Instrument Tranche Four [Member] Debt instrument tranche four. Income Statement Location [Axis] Income Statement Location Variable lease costs Variable Lease, Cost 2027 Long-Term Debt, Maturity, Year Three Increase decrease in operating lease liabilities. Increase Decrease In Operating Lease Liabilities Operating lease liabilities Restricted Stock, Value, Shares Issued Net of Tax Withholdings Issuance of common stock upon vesting of RSUs, net of tax withholdings, value Contract with customer liability with related party. Deferred revenue - related party, Balance at end of period Deferred revenue - related party, Balance at beginning of period Contract With Customer Liability With Related Party Long-Term Debt, Type [Axis] Long-term Debt, Type Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Line of Credit Facility, Lender [Domain] Line of Credit Facility, Lender Fair Value, Inputs, Level 2 [Member] Level 2 [Member] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Phase three study. Phase Three Study [Member] Phase 3 [Member] Long-Term Debt, Gross Carrying value of debt Depreciation, Depletion and Amortization Depreciation and amortization expense Depreciation, Depletion and Amortization, Total Product and Service [Axis] Additional default interest rate per annum apply to all obligations owed under the agreement. Additional Default Interest Rate Per Annum Apply to all Obligations Owed under the Agreement. Additional default interest rate Title of 12(b) Security Title of 12(b) Security AstraZeneca, Incorporated. Astra Zeneca Incorporated [Member] AstraZeneca Inc. [Member] Lease Contractual Term [Axis] Prime Rate [Member] Prime Rate [Member] Total collaboration (profit) loss sharing - related party Total collaboration (profit) loss sharing - related party Collaboration (profit) loss sharing - related party Collaboration (profit) loss sharing - related party Profit (loss) from research agreement related party. Profit (Loss) from Research Agreement Related Party Investments [Domain] Accounting Standards Update [Axis] Accounting Standards Update Tranche c warrant. Tranche C Warrant [Member] Tranche C Warrant [Member] Market equity offering. Market Equity Offering [Member] Market Equity Offering [Member] Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Amortization of debt issuance costs Amortization of Debt Issuance Costs Hercules Capital, Inc. Hercules Capital Inc [Member] Hercules Capital, Inc. [Member] Term loan facility Long-Term Line of Credit Long-Term Line of Credit, Total Other Income [Member] Other Income [Member] Long-Lived Tangible Asset [Domain] Long-Lived Tangible Asset Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Inventories Inventories Increase (Decrease) in Inventories Increase (Decrease) in Inventories, Total Non-current liability. 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Debt Instrument Tranche Three [Member] Tranche A-3 [Member] Common Stock, Shares, Outstanding Ending balance, shares Beginning balance, shares Common stock, shares outstanding Risk free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Forfeited Volatility Derivative Liability Expected Volatility Derivative LiabilitDerivative Liability Expected Volatilityy Expected Volatility Less: stock-based compensation Deferred Compensation Arrangement with Individual, Allocated Share-Based Compensation Expense Income Statement Location [Domain] Income Statement Location Weighted average exercise price of stock options granted Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Granted Document Type Document Type Tranche A-1 Loan [Member] Tranche A-1 Loan [Member] Tranche A-1 loan. Net cash (used in) provided by investing activities Net Cash Provided by (Used in) Investing Activities Operating lease, remaining term Lessee Operating Lease Remaining Term Of Contract Lessee operating lease remaining term of contract. Document Quarterly Report Document Quarterly Report Counterparty Name [Domain] Counterparty Name Employee Benefits and Share-Based Compensation Employee share based compensation expense Income (loss) attributable to common stockholders - basic Net Income (Loss) Available to Common Stockholders, Basic Loss attributable to common stockholders - basic Loss attributable to common stockholders - basic Proceeds from at the market equity offering, net of issuance costs Proceeds from issuance of common stock from at the market equity offering. Proceeds From Issuance of Common Stock From at the Market Equity Offering Cambridge Massachusetts [Member] Cambridge Massachusetts [Member] Cambridge massachusetts. Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Number of Shares, Forfeited Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Irvine, CA [Member] Irvine, California [Member] Irvine, California. Entity Filer Category Entity Filer Category Percentage increase in net sales rate Percentage Increase in Net Sales Rate Percentage increase in net sales rate. Deferred revenue - related party Contract with customer liability noncurrent related party. Contract With Customer Liability Noncurrent Related Party Balance Sheet Location [Domain] Balance Sheet Location Topic 808 [Member] Accounting Standards Update 2018-18 [Member] Impairment loss Operating Lease, Impairment Loss Currency translation adjustment Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Total Performance Based Restricted Stock Units (PSUs) [Member] Performance Based Restricted Stock Units (PSUs) [Member] Spring House, Pennsylvania. Spring House, Pennsylvania [Member] Spring House, PA [Member] Variable Rate [Axis] Variable Rate Non-cash operating lease cost. Non Cash Operating Lease Cost Non-cash operating lease cost Short-Term Investments Short term investments Short-term Investments, Total Schedule of Collaboration Profit (Loss) Research agreement related party [Table Text Block] Tabular disclosure of collaboration (profit) loss sharing-related party. Nonoperating Income (Expense) Total other expense, net Capital Expenditures Incurred but Not yet Paid Property and equipment purchases included in accounts payable and accrued expenses Liabilities Total liabilities Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Unvested restricted stock units. Unvested Restricted Stock Units [Member] Unvested Restricted Stock Units [Member] Impairment loss Asset Impairment Charges Asset Impairment Charges, Total Total stockholders' deficit Equity, Attributable to Parent Ending balance Beginning balance Net income (loss) Net loss Net loss attributable to common stockholders Other income (expense): Nonoperating Income (Expense) [Abstract] Collaboration payable - related party (Note 16) Transaction price allocated under collaborative arrangement Transaction price allocated under collaborative arrangement Transaction price allocated under collaborative arrangement Business Description and Basis of Presentation [Text Block] Nature of the Business and Basis of Presentation Cash and Cash Equivalents [Domain] Cash and Cash Equivalents Percentage of commission on sale of common stock. Percentage Of Commission On Sale Of Common Stock Percentage of commission on sale of common stock Convertible Debt [Member] Statement of Financial Position [Abstract] Weighted-average shares outstanding - diluted Weighted-average shares outstanding - diluted Weighted average common shares outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted Thereafter Long-Term Debt, Maturity, after Year Four Long-Term Debt, maturity, after year four. Impairment of long-lived assets Impairment of Long-Lived Assets to be Disposed of Credit Facility [Axis] Credit Facility Debt Securities, Available-for-Sale, Amortized Cost Amortized Cost Weighted average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Outstanding restructuring liabilities Remaining liability included in accrued expenses and other current liabilities Restructuring Reserve, Current Use of Estimates, Policy [Policy Text Block] Use of Estimates Percentage of performance-based stock options vesting Percentage of Performance-Based Stock Options Vesting Percentage of performance-based stock options vesting. Income Tax Disclosure [Text Block] Income Taxes Weighted Average Exercise Price, Ending Balance Weighted Average Exercise Price, Beginning Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Share of VOWST net loss Share of VOWST net loss Share of Related Party Net Loss Share of related party net loss. Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Basic and Diluted Net Loss Per Share Attributable to Common Stockholders Maximum development milestone payments to be received. Maximum Development Milestone Payments To Be Received Maximum development milestone payments to be received Original Credit Facility [Member] Original Credit Facility. March 2022 member March 2022 [Member] March 2022 [Member] Leasehold Improvements [Member] Leasehold Improvements [Member] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Fair Value Disclosures [Abstract] Schedule of Collaboration Profit (Loss) Schedule of Business Acquisitions, by Acquisition [Table Text Block] Level 2 [Member] Fair Value Hierarchy and NAV [Axis] Measurement Frequency [Domain] Measurement Frequency Other Long Term Liabilities [Member] Other Noncurrent Liabilities [Member] Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment, Total Type of Restructuring [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Number of Shares, Vested Number of Shares, Vested Number of shares, vested Issuance of common stock, net of issuance costs, shares Stock Issued During Period, Shares, New Issues Common stock, shares issued Employee-related Liabilities, Current Payroll and payroll-related costs Employee-related Liabilities, Current, Total Business Acquisition [Axis] Accrued expenses and other current and long-term liabilities (4) Increase (decrease) in accrued expenses and other current and long-term liabilities. Increase Decrease In Accrued Expenses And Other Current And Long Term Liabilities Income Tax Disclosure [Abstract] Percentage of prepayment amount during first year following closing date. Percentage Of Prepayment Amount During First Year Following Closing Date Percentage of prepayment amount during first year